Jayne: Any one you walk away from, right? Long as we got the goods, I call this a win.
Mal: Right. We win.

Pilot

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Jayne: All of you! You think there’s someone just gonna drop money on ya?! Money they could use?! Well, there ain’t people like that. There’s just people like me.

Mal: Patients were cynical, and not responding, and we couldn’t bring ’em back.
Simon: They were cyanotic…

Tracey: When you can’t run, you crawl. And when you can’t crawl, when you can’t do that…
Zoe: … you find someone to carry you.

Inara: I’d have to say, this is the first time we’ve had a preacher on board.
Book: Well, I wasn’t expecting to see a state official either. Ambassador…I’m missing something funny.
Kaylee: Not so funny.
Inara: Ambassador is Mal’s way of—
Mal: She’s a whore, Shep.

Jayne: Your move.
Zoe: That’s a bold move.
Mal: I live on the edge.