Mal: Patients were cynical, and not responding, and we couldn’t bring ’em back.
Simon: They were cyanotic…

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Jayne: All of you! You think there’s someone just gonna drop money on ya?! Money they could use?! Well, there ain’t people like that. There’s just people like me.

Jayne: Hell, I don’t know. If I wanted schooling, I’d-a gone to school.

Inara: I’d have to say, this is the first time we’ve had a preacher on board.
Book: Well, I wasn’t expecting to see a state official either. Ambassador…I’m missing something funny.
Kaylee: Not so funny.
Inara: Ambassador is Mal’s way of—
Mal: She’s a whore, Shep.

Jayne: Your move.
Zoe: That’s a bold move.
Mal: I live on the edge.

Mal: No one’s gonna hurt you.
Survivor: No. No mercy. No!
Mal: Any more than we already did.