I’ve heard that it’s possible to grow up – I’ve just never met anyone who’s actually done it. Without parents to defy, we break the rules we make for ourselves. We throw tantrums when things don’t go our way, we whisper secrets with our best friends in the dark, we look for comfort where we can find it, and we hope .. against all logic, against all experience. Like children, we never give up hope.

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Dr. Alex Karev: For a kiss to be really good, you want it to mean something. You want it to be with someone you can’t get out of your head, so that when your lips finally touch you feel it everywhere. A kiss so hot and so deep you never want to come up for air. You can’t cheat your first kiss. Trust me, you don’t want to. Cause when you find that right person for a first kiss, it’s everything.

Dr. Christina Yang: I can’t straddle another ego right now, I’m already doing the splits.

Dr. Meredith Grey: At the end of the day, there are some things you just can’t help but talk about. Some things we just don’t want to hear, and some things we say because we can’t be silent any longer. Some things are more than what you say, they’re what you do. Some things you say cause there’s no other choice. Some things you keep to yourself. And not too often, but every now and then, some things simply speak for themselves.

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Dr. Meredith Grey: Okay here it is. Your choice. It’ s simple. Her or me. And I’m sure she’ s really great. But Derek, I love you, in a really, really big – pretend to like your taste in music, let you eat the last piece of cheesecake, hold a radio over my head outside your window – unfortunate way that makes me hate you, love you. So pick me. Choose me. Love me.

Bring the Pain (season 2, episode 5)