See, once in a while, once in a blue moon, people will surprise you. And once in a while, people may even take your breath away.

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Denny Duquette: I’ve been lying in this bed for close to a year, and I’ve had a lot of time to look back on my life. And the things that I remember best – those are the things I wasn’t supposed to do and I did them anyway. The thing is, life is too damn short to be following these rules.

Merideth: McSteamy.
George: Merideth.
Merideth: McSteamy! Whoo hoo!
Mark: So is that what you’re calling me now, McSteamy?
Merideth: Yeah, but I don’t think you’re supposed to know that.
Mark: So, how’s my favorite dirty mistress?
Merideth: Haven’t you heard? Now I’m an adulteress whore.

Dr. Meredith Grey: How do you know when how much is too much? Too much too soon. Too much information. Too much fun. Too much love. Too much to ask… And when is it all just too much to bear?

I’ve heard that it’s possible to grow up – I’ve just never met anyone who’s actually done it. Without parents to defy, we break the rules we make for ourselves. We throw tantrums when things don’t go our way, we whisper secrets with our best friends in the dark, we look for comfort where we can find it, and we hope .. against all logic, against all experience. Like children, we never give up hope.

Dr. Alex Karev: For a kiss to be really good, you want it to mean something. You want it to be with someone you can’t get out of your head, so that when your lips finally touch you feel it everywhere. A kiss so hot and so deep you never want to come up for air. You can’t cheat your first kiss. Trust me, you don’t want to. Cause when you find that right person for a first kiss, it’s everything.