Anderson: Never mind that, we found the case! According to “someone,” the murderer has the case, and here we found it, in the hands of our favorite psychopath.
Sherlock Holmes: I’m not a psychopath, Anderson, I’m a high-functioning sociopath. Do your research.

A Study in Pink (season 1, episode 1)

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Watson: Who are you?
Mycroft: An interested party.
Watson: Interested in Sherlock? Why? I’m guessing you’re not friends.
Mycroft: You’ve met him. How many friends do you imagine he has?

A Study in Pink (season 1, episode 1)

Anderson: So we can read her emails, so what?
Sherlock Holmes: Anderson, don’t talk out loud. You lower the IQ of the entire street.

A Study in Pink (season 1, episode 1)