People
[The Guide] says that the effect of a Pan Galactic Gargle Blaster is like having your brains smashed out by a slice of lemon wrapped round a large gold brick.
— Douglas Adams ‧ The Hitchhiker's Guide to the Galaxy

Behind the line May contain spoilers.
Our reading
An editorial interpretation.
This wildly exaggerated comparison describes an overwhelming effect by likening it to a bizarre, almost nonsensical act of violence, brains smashed by a lemon-wrapped brick. The absurd specificity of the image, oddly precise yet utterly impossible, is what makes the comparison so memorably funny.
Context reviewed