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C'mon Miley. I know guys. Sooner or later he'll get tired of chasing someone who's not chasing him back.
— Rob Ray Stewart

Behind the line May contain spoilers.
Our reading
An editorial interpretation.
The speaker predicts that this man's pursuit will fade without interest in return. Claiming to know guys gives the prediction a confident tone. The remark asks Miley to consider how long someone might keep chasing a person who does not respond in kind.
Context reviewed