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How are you doing out there in Marlboro country?
— Robert ‧ The Horse Whisperer

Behind the line May contain spoilers.
Our reading
An editorial interpretation.
The speaker checks how someone is doing in a place dubbed 'Marlboro country'. The phrase gives the location a recognizable, stylized label rather than a precise address. Read as teasing, the question asks about an experience while gently commenting on the surroundings in which it happens.
Context reviewed