People
Life is so short. Why waste a single day of it doing something that doesn’t matter, that doesn’t try to do something big?
— Dean Kamen

Behind the line May contain spoilers.
Our reading
An editorial interpretation.
The speaker connects life's brevity with a demand to attempt something significant. Each day becomes valuable because the available time is limited. The question expresses an ambitious standard for worthwhile effort, encouraging purposeful action without identifying one particular achievement that everyone should pursue.
Context reviewed