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I’m a very tolerant man, except when it comes to holding a grudge.
— Popeye · Popeye

Behind the line May contain spoilers.
Our reading
An editorial interpretation.
The speaker announces broad tolerance, then immediately makes an exception for holding a grudge. That exception undermines the flattering self-description. The joke lies in claiming an easygoing virtue while reserving room for the very resentment that seems to contradict it.
Context reviewed