Characters
Don't tell me those brain-dead lowlifes are calling me again.
— Mel ‧ Clueless
Behind the line May contain spoilers.
Our reading
An editorial interpretation.
The speaker reacts with weary disgust at being phoned once more, insulting the callers as mindless lowlifes. The plea 'Don't tell me' suggests they hope it isn't true, and 'again' marks how tiresome the repetition has already become. The tone is exasperated and contemptuous.
Context reviewed