A miniature dining table crowded with dishes at one end and a single place setting at the other on a dark green background.

Original artwork, not a still

Comic Book Guy

Oh loneliness and cheeseburgers are a deadly combination.

— The Simpsons • 1989

Behind the line

What it means

Our interpretation.

The speaker declares, with mock gravity, that loneliness and cheeseburgers together are deadly. The joke treats comfort eating as a lethal combination, letting a wry remark quietly carry a real note of sadness about solitude.

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